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Nowadays there is no satisfactory treatment for premature ejaculation despite its obvious need. Conservative therapy for premature ejaculation is based on the sensory decrement of the glans penis with topical anesthetics. Pharmacological effects on serotonin receptors of the central nervous system are also used with selective serotonin reuptake inhibitors.

Currently, most surgical treatments for premature ejaculation are targeted at reducing the sensitivity of the penis.

The most common of these is selective dorsal neurotomy (SDN) – transection of penile nerves.

The method is effective, but non-reversible. It means, that SDN could leads to total lifelong anesthesia of the penis with risk of erectile dysfunction.